Under what condition can a registered pharmacist make changes to a patient’s drug therapy?

A registered pharmacist can make changes to a patient's drug therapy if authorized in a protocol. This means that there are established guidelines or agreements in place that allow a pharmacist to modify a patient’s medication regimen in a responsible and controlled manner, typically as part of a collaborative practice agreement with a physician.

Protocols help ensure that any adjustments to a patient's medication are safe and appropriate, based on specific conditions or criteria that are outlined in the agreement. These protocols are developed to enhance patient care and allow for flexibility in managing drug therapies, while still adhering to regulations and ensuring patient safety.

On the other hand, making changes at the request of a patient without the appropriate authority may not be permissible, as pharmacists must operate within the scope defined by law and professional practice guidelines. Similarly, while the availability of a generic drug may influence a pharmacist's decisions regarding cost-effectiveness or patient preference, it does not provide a legal basis for altering therapy. Lastly, a pharmacist cannot automatically make changes if the doctor is unavailable, as this could compromise the clinical integrity of the patient's care.